The edge plasma region, located between the core plasma and the solid elements of the tokamak, plays a key role in both plasma confinement properties (H-mode) and heat transfer from the core to the wall - two major challenges for the success of ITER. The geometrical complexity of the magnetic equilibrium and of the components facing the plasma, and the multitude of physical processes at play, from turbulence and out-of-equilibrium thermodynamics to the atomic physics of plasma-wall interaction, lead to a very high level of complexity and to a large number of physics and modeling questions that the Institute is addressing. One of the challenges of the physics of plasma-wall interaction is to lower the energy flux at the walls to ensure the survival of the materials while guaranteeing the performance of the plasma at the core. To this end, the Institute is developing a hierarchy of theoretical and numerical models, as well as experimental diagnostics, to better characterize the non-linear and coupled effects of turbulence, the main source of transport transverse to the magnetic field, and of the particles resulting from interaction with the wall (neutrals, impurities, etc.), to which the energy of the plasma particles is transferred.